Extraordinarily Easy to use, Modular HPLC
Each Merit system incorporates the proven, reliable, consistent, high specification, ultra-low drift and durable performance of the trusted Cecil pumps and UV/Visible detectors.
Each system is fully PC controlled, using Merit software, to achieve and save high quality chromatograms. Automatic integration is provided, without the need for further baseline adjustment. Qualitative work is remarkably easy. The fast checking of multi-component samples is easy.
System choices include a CE 4403 UV/Visible detector, a DAD WaveQuest detector, an isocratic CE 4401 pump, a CE 4402 binary pump and a column heater/chiller. Biocompatible options are available.
Set-up of the system hardware is fast, the pump and detector modules each plug into the USB ports of a PC or laptop. The Merit software only takes a few seconds to load and just a few minutes to master. Save HPLC methods and store chromatograms within Merit software or elsewhere on the PC , network or portable drive etc.
In the case of the Merit PC software, chromatograms may be copied and pasted into other software programmes, such as Word or PowerPoint.
All the numerical data points captured within each chromatogram is saved. In two key strokes, data may be manually copied and pasted into Excel or other software spreadsheets.
GLP data such as time, date, serial number of the detector etc. are automatically displayed. Again, data may be copied and pasted into Word, PowerPoint or other software packages.
In addition, the Merit software contains a spacious library. Once a chromatogram is created, it may be saved into the library. In two clicks of the mouse, subsequent chromatograms, may then be compared with the saved chromatograms.
When any two chromatograms are automatically compared with each other, a numerical match index is automatically created. Within a few seconds, a league table of comparable chromatograms is created. This is such a useful facility when performing initial method development and routine elutions.
The minimum PC requirements for Merit PC software are:-
- Personal Computer with Pentium class processor
- Pentium 200 MHz or better
- Microsoft Windows 95, 98, Me, 2000, NT, XP, 7, 8 or later
- Free hard-drive space required: 2 MB
- CD-ROM drive
- XGA or higher resolution monitor
- Monitor resolution 1024 x 768 or better
- Microsoft Mouse or compatible pointing device
- Two available USB ports
These Merit HPLC systems will make life so much easier for so many chemical, biological and materials analysts in so many fields. Multi compound screening scientists, scientists performing initial method development, production scientists, process development chemists, lecturers, teachers and novices, in fact everyone one who wants high impact quick and easy HPLC, will find that a Merit is just right for their needs.
The Merit HPLC systems demonstrate the ultimate in HPLC simplicity. Just inject and go.


Merit HPLC Specifications
Isocratic HPLC Pump CE 4401
Flow Rate |
0.001 to 10mL/min in 0.001 steps |
Flow Reproducibility |
Better than 0.1% |
Maximum Pressure |
40MPa = 400 bar |
Over Pressure Cut-out |
Adjustable between 3 and 40MPa |
Low Pressure Cut-out |
Adjustable between 0 and 40MPa |
Material in contact with fluids |
Ceramic inserts - biocompatible |
|
Check valves – ruby and sapphire |
Pulsation |
Better than ±0.5% at 2mL/min |
PC connection |
USB port |
Binary Low Pressure Mixing HPLC Pump CE 4402
Flow Rate |
0.001 to 10mL/min in 0.001/min increments |
Pressure Range |
0-40MPa over flow range |
Flow Accuracy |
<±0.5% |
Flow Precision |
<0.1% RSD |
Pressure Pulsation |
<±0.5% at 2mL/min |
Gradient Forming |
Binary gradient low pressure mixing and isocratic high pressure operation |
Gradient Control |
Using proprietary high-speed proportioning valves |
Gradient Precision |
Typically 0.2% RSD at 1mL/min |
Material in contact with fluids |
Ceramic inserts, ruby and sapphire check valves, PEEK |
PC connection |
USB port |
UV-Visible Detector CE 4405
Optical System |
Double beam with 1200 lines/mm grating monochromator |
Wavelength Range |
190-700nm |
Wavelength Accuracy |
± 1nm |
Wavelength Precision |
± 0.1nm |
Optical Bandwidth |
8nm |
Straylight |
< .02%, 220nm |
Lamp |
Deuterium lamp with elapsed time indicator |
Absorbance Range |
0.001 to 2A full scale in 11 ranges |
Time Constant |
0.1, 0.2, 0.5, 1, 2, 5 and 10 seconds |
Method Storage |
For up to 30 methods, security protected |
Noise |
± 1 x 10-5 A peak to peak, 220nm, 2s time constant |
Drift |
± 1 x 10-4 A/hour at constant temperature |
Linearity |
Better than 1%, 0.001 – 2A |
Automatic Power-up/off |
Pre-programmed top save warm-up time |
Sample Flow Cell |
8µL x 10mm pathlength |
Refractive Index Sensitivity |
< ± 5 x 10-4 A, water to methanol at 350nm |
Flow Rate Sensitivity |
< ± 3.5 x 10-3 A, for flow change 1-2mL/min, 300nm |
PC connection |
USB port |
WaveQuest D.A.D. Ultra Fast Scanning Detector CE 4403
Optical System |
Double beam |
Monochromator |
With 1200 l/mm holographic grating |
Wavelength Range |
190-700nm |
Optical Bandwidth |
4nm – constant |
Digital Resolution |
1nm |
Wavelength Accuracy |
1nm |
Wavelength Reproducibility |
0.1nm |
Absorbance Range |
0 to 3A |
Scan Speeds |
Up to 1000nm/s |
Baseline Flatness |
± 0.002A over most of range |
Straylight |
<0.02% at 220nm and 340nm |
Noise |
< ±0.5 x 10–5 A at 230nm, 2s air test cell |
Drift |
< ±0.5 x 10–4 A at 230nm, using air test cell |
Calibration and Test |
Automatic at switch-on |
Number of Peak Scans |
Up to 100 peaks for any single elution |
Multiple Scans of a Peak |
Up to 8 scans of any peak |
Scan Trigger |
At start, set Absorbance value, point of inflection or at maximum |
Scan Storage |
Up to 100, password protected |
Method Storage |
Up to 30 methods, password protected |
Heated Oven CE 4407
Temperature Range |
Ambient to 85ºC |
Temperature and Set Point |
3 digit bright LED display |
Temperature Readout Resolution |
0.1ºC |
Temperature Stability |
± 0.01ºC |
Number of Columns |
3 up to 25cm long with pre-columns |
Heating Rate |
30 mins to set point of 65ºC (ambient 25ºC) |
Stabilising Time |
Negligible when set point reached |
Leak Detection |
Vapour detector – adjustable shut down level |
Autosampler CE 4408
Carousel capacity |
50 vials, 2mL |
Loop sizes |
10μL - 200μL |
Injection valve |
Rheodyne 7900-000 |
Sample loop flush |
Operator selectable |
Volume reproducibility |
Better than 0.05% |
Carry over (with wash) |
Better than 0.005% |
Replicate injection |
up to 15 |
Cycle time |
12s minimum |
Solvent Degasser CE 4020
Number of flow channels |
2 |
Maximum Flowrate |
10mL/min |
Materials Contacting Solvents |
PEEK, glass filled PTFE, Teflon AF |
Gas removal |
To better than 1ppm at 1mL/min |
Isocratic HPLC Pump CE 4401
Flow Rate |
0.001 to 10mL/min in 0.001 steps |
Flow Reproducibility |
Better than 0.1% |
Maximum Pressure |
40MPa = 400 bar |
Over Pressure Cut-out |
Adjustable between 3 and 40MPa |
Low Pressure Cut-out |
Adjustable between 0 and 40MPa |
Material in contact with fluids |
Ceramic inserts - biocompatible |
|
Check valves – ruby and sapphire |
Pulsation |
Better than ±0.5% at 2mL/min |
PC connection |
USB port |
Isocratic HPLC Pump CE 4401
Flow Rate |
0.001 to 10mL/min in 0.001 steps |
Flow Reproducibility |
Better than 0.1% |
Maximum Pressure |
40MPa = 400 bar |
Over Pressure Cut-out |
Adjustable between 3 and 40MPa |
Low Pressure Cut-out |
Adjustable between 0 and 40MPa |
Material in contact with fluids |
Ceramic inserts - biocompatible |
|
Check valves – ruby and sapphire |
Pulsation |
Better than ±0.5% at 2mL/min |
PC connection |
USB port |
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非常簡單易用,模塊化高效液相色譜法
每個優點系統采用了經過驗證的,可靠的,一致的,高規格,超低漂移和信任塞西爾的耐用性能泵和紫外/可見光檢測器。
每個系統完全電腦控制,采用優異的軟件,來實現和保存高質量的色譜圖。自動一體化設置,而不需要進一步的基線調整。定性的工作是非常容易的。多組分樣品的快速的檢查也容易。
系統選擇包括CE 4403紫外/可見光檢測器,二極管陣列檢測器WaveQuest ,等度CE 4401泵, CE 4402二元泵和色譜柱加熱器/冷卻器。生物相容性可供選擇。
建立了系統的硬件速度快,泵和檢測每個模塊插入到PC或筆記本電腦的USB端口。優異的軟件只需要幾秒鐘加載,只是幾分鐘的時間來掌握。保存的HPLC方法,并在優異的軟件或PC ,網絡或可移動驅動器等其他地方商店色譜圖
在優異的PC軟件的情況下,色譜圖可以復制并粘貼到其他軟件程序,如Word或PowerPoint 。
所有每個色譜圖中捕獲的數值數據點被保存。在兩個關鍵筆畫,數據可以手動復制并粘貼到Excel或其他電子表格軟件。
GLP數據,如時間,日期,檢測器的序列號等被自動顯示。同樣,數據可以被復制并粘貼到Word中, PowerPoint或其他軟件包。
此外,優異的軟件包含了一個寬敞的圖書室。一旦色譜創建時,它可被保存到庫中。在兩次點擊鼠標,則后續的色譜圖,然后可以與所保存的色譜圖相比較。
當任意兩個色譜圖會自動相互比較,數值匹配索引被自動創建。幾秒鐘內,可比較色譜圖的名次表被創建。這是多么有用的工具執行初始方法開發和日常洗脫時。
為優異的PC軟件的最低PC要求是: - •個人電腦與奔騰級處理器 • Pentium 200 MHz或更好 •微軟Windows 95 , 98 , ME,2000 , NT,XP , 7 , 8或更高版本 •所需的可用硬盤空間: 2 MB • CD -ROM驅動器 • XGA或更高分辨率的顯示器 •顯示器分辨率1024× 768或更高 • Microsoft鼠標或兼容的指針設備 •兩個可用的USB端口
這些優異的HPLC系統將讓生活變得更輕松了這么多的化學,生物和材料分析在如此眾多的領域。多化合物篩選的科學家,執行初始方法開發,生產的科學家,工藝開發的化學家,講師,教師和新手,其實大家一個誰愿意高抗沖快速簡便高效液相色譜科學家,會發現一個優點是正好適合他們的需求。
優異的HPLC系統表現出極致的高效液相色譜法簡單。剛剛注入而歸。
技術規格:
等度HPLC泵CE 4401 流量0.001〜 10ml/min時0.001步驟 流量重復性優于0.1% 最大壓力為40MPa = 400吧 過壓開孔可調節3至為40MPa 低壓切出可在0和為40MPa 材料與液體陶瓷刀片的接觸 - 生物相容性 止回閥 - 紅寶石和藍寶石 脈動小于± 0.5 %提升以2mL/min PC連接USB端口
二元梯度混合HPLC泵CE 4402 流量0.001〜 10ml/min時在0.001/min增量 壓力范圍0 -為40MPa以上流量范圍 流量精度< ± 0.5 % 流量精度< 0.1 %RSD 以2mL/min壓力脈動< ± 0.5 % 梯度形成二元梯度低壓混合和等度高壓操作 梯度控制使用專有的高速比例閥 梯度精度一般為0.2 %,相對標準偏差為1ml/min 材料與液體陶瓷刀片,紅寶石和藍寶石止回閥, PEEK接觸 PC連接USB端口
紫外 - 可見光檢測器CE 4405 光學系統雙光束1200線/ mm的光柵單色儀 波長范圍190- 700nm的 波長精度± 1nm的 波長精度±為0.1nm 光學帶寬為8nm 雜散光< .02 % ,220納米 燈氘燈與經過時間指示器 吸光度范圍0.001〜 2A滿量程的11范圍 時間常數0.1,0.2, 0.5,1, 2,5秒和10秒 方法存儲多達30的方法,安全保護 噪聲± 1 ×10-5峰值到峰值,220納米, 2秒的時間常數 漂移± 1× 10-4 /小時恒溫 線性度優于1% , 0.001 - 2A 自動Power-up/off預編程的頂級節省預熱時間 樣品流通池8μL ×10毫米光程 折射率靈敏度< ± 5× 10-4 ,水與甲醇在350nm 流量靈敏度< ± 3.5× 10-3 ,用于流量變化1-2mL/min , 300nm的 PC連接USB端口
WaveQuest D.A.D.超快速掃描探測器CE 4403 光學系統雙光束 單色儀采用1200條升/毫米全息光柵 波長范圍190- 700nm的 光學帶寬4nm的 - 恒 數字分辨率為1nm 波長準確度為1nm 波長重復性為0.1nm 吸光度范圍:0〜 3A 掃描速度高達1000nm的/秒 基線平直度± 0.002A在大部分范圍內 雜散光<在220nm和340nm的0.02 % 噪聲< ± 0.5× 10-5處為230nm ,2S空氣測試單元 漂移< ± 0.5× 10-4在230nm處,用空氣測試單元 校準和測試時自動接通 掃描次數多達100個峰任何單一洗脫 峰值高達8掃描任何峰多次掃描 掃描觸發器在啟動,設定吸光度值,拐點或最大 掃描存儲最多100 ,密碼保護 方法存儲多達30個方法,密碼保護
柱溫箱 CE 4407 溫度范圍室溫至85℃ 溫度和設定點3位高亮LED顯示屏 溫度讀數分辨率0.1 ºC 溫度穩定性± 0.01 ºC 列高達3到25cm長,預列數 升溫速率30分鐘,以設定點為65 ℃(室溫25 ℃) 穩定價格的時間可以忽略不計,當設定點達到 泄漏檢測蒸氣檢測儀 - 可調節的關機水平
自動進樣器CE 4408 旋轉盤 容量50瓶, 2毫升 環尺寸10μL - 200μL 進樣閥的Rheodyne 7900-000 樣品環沖洗操作可選 體積重現性優于0.05% 結轉(含洗)優于0.005 % 復制注射高達15 周期時間最短12秒
溶劑脫氣機CE 4020 流動通道2的數 最大流速10ml/min時 物料接觸溶劑聚醚醚酮,玻璃填充聚四氟乙烯,聚四氟乙烯自動對焦 氣體脫除要低于1PPM更好地為1mL/min
配置表:

The following are included as standard, within each Merit HPLC system: All system modules Injection valve and loop Interconnection and power cables. Column and valve panel where appropriate. Pipes and tubing. Sample injection syringe . Solvent bottles with drilled lids. Solvent inlet filter. Standard flowcell
以下是作為標準,每優異HPLC系統中: 所有的系統模塊 進樣閥和循環 互連電纜和電源線。柱和閥板在適當情況下。 管道和管件。 樣品注射器。 溶劑瓶與蓋鉆。溶劑入口過濾器。 標準流通池。
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